研究领域(方向)
生化分析与分子诊断,核酸、蛋白质生物标志物的高灵敏度分析,阿尔茨海默病早期诊断
教育工作经历:
2020/09-至今,拉斯维加斯网上总站基础与转化医学研究所,讲师
2017/09-2020/06,陕西师范大学,分析化学,博士
2014/09-2017/06,陕西师范大学,化学生物学,硕士
2010/09-2014/06,合肥工业大学,生物与食品工程学院,学士
科研项目:
(1)国家自然科学基金青年项目,22104122,外周血中阿尔茨海默病蛋白标志物的数字式免疫多重分析新方法研究,2022/01-2024/12,30万元,主持。
(2)陕西省教育厅专项科研计划项目,21JK0895,2021/01-2022/12,2万元,主持。
(3)陕西省卫生健康科研基金项目,2021D046,2021/04-2023/04,1万元,主持。
(4)西安市科学技术局自然科学基金项目,2025JH-ZRKX-0026,2025/01-2027/12,5万元,主持。
代表性论著:
(1)Yan Qi, Junyue Sun, Shan Wang, Wei Ren, and Chenghui Liu. Mix-and-Read Digital MicroRNA Analysis Based on Flow Cytometric Counting of Target-Clicked Nanobead Dimer. Anal. Chem. 2024, 96, 13734−13741
(2)Yan Qi, Yuqing Zhai, Wenjiao Fan, Wei Ren, Zhengping Li, and Chenghui Liu. Click Chemistry-Actuated Digital DNA Walker Confined on a Single Particle toward Absolute MicroRNA Quantification. Anal. Chem. 2021, 93, 1620-1626.
(3)Yan Qi, Xiaohui Lu, Qinya Feng, Wenjiao Fan, Chenghui Liu and Zhengping Li. An Enzyme-Free MicroRNA Assay Based-on Fluorescence Counting of Click Chemical Ligation-Illuminated Magnetic Nanoparticles with Total Internal Reflection Fluorescence Microscopy. ACS Sens. 2018, 3, 2667-2674.
(4)Yan Qi, Liying Qiu, Wenjiao Fan, Chenghui Liu and Zhengping Li. An Enzyme-Free Flow Cytometric Bead Assay for the Sensitive Detection of MicroRNAs Based on Click Nucleic Acid Ligation-Mediated Signal Amplification. Analyst, 2017, 142, 2967-2973.
(5)Wenjiao Fan, Yan Qi, Xiaohui Lu, Wei Ren, Chenghui Liu and Zhengping Li. An Emulsion-Free Digital Flow Cytometric Platform for the Precise Quantification of MicroRNA Based on Single Molecule Extension-Illuminated Microbeads (dFlowSeim). Chem. Commun. 2020, 56, 7179-7182.
(6)Wenjiao Fan, Yan Qi, Liying Qiu, Pan He, Chenghui Liu and Zhengping Li. Click Chemical Ligation-Initiated On-Bead DNA Polymerization for the Sensitive Flow Cytometric Detection of 3′-Terminal 2′-O-Methylated Plant MicroRNA. Anal. Chem. 2018, 90, 5390-5397.
(7)Liping Zhu, Desheng Chen, Xiaohui Lu, Yan Qi, Pan He, Chenghui Liu and Zhengping Li. An Ultrasensitive Flow Cytometric Immunoassay Based on Beadsurface-Initiated Template-Free DNA Extension. Chem. Sci. 2018, 9, 6605-6613.
联系方式:
电子邮箱:yanqi@xiyi.edu.cn
联系地址:陕西省西安市未央区辛王路1号